Conference Program

DAY 1

8.00 – REGISTRATION

8.25 – OPENING by Dr. Sofie Lindgren Christiansen

8.30 – NON-INVASIVE PREDICTION OF FETAL BLOOD GROUPS

Non-invasive Fetal Antigen Genotyping
Dr. Åsa Hellberg (Sweden)

Non-invasive Prediction of Fetal Blood Groups:
A US Perspective
Prof. Kenneth J Moise (USA)

Oral Presentation (5 min)
A. Non-invasive fetal RHD genotyping in D- (RH:-1) patients with RHD genomic sequences: Retrospective study over 11 years. Cécile Toly-Ndour (France)

Chairs: Prof. Ellen van der Schoot and Dr. Frederik Banch Clausen

10.00 – Coffee Break

10.30 – NON-INVASIVE PREDICTION OF FETAL BLOOD GROUPS (continued)

Fighting Rh Disease: An African Perspective from AFRICARhE
Prof. Ellen van der Schoot (The Netherlands)

Oral Presentations (5 min)
B. Clinical Validation of a Prenatal Cell-Free DNA Screening Test for Fetal RHD in a Large U.S. Cohort. Samantha Leonard (USA)
C. TBA

Chairs: Dr. Åsa Hellberg and Dr. Frederik Banch Clausen

11.45 – Lunch Break

12.45 – POSTER SESSION

13.45 – NON-INVASIVE PRENATAL TESTING AND DIAGNOSIS

Embryo cfDNA: From Research to Clinical Application to Improve IVF Outcomes
Dr. Carmen Rubio Lluesa (Spain)

Oral Presentations (5 min)
D. The EXPAND Study: Validation of a Single-Gene Noninvasive Prenatal Screening Test. Vivienne Souter (USA)
E. Whole genome paternal uniparental disomy identified through prenatal SNP-based cell free-DNA screening. Peter Benn (USA)

Chairs: Dr. Natalie Chandler and Dr. Sofie Lindgren Christiansen

15.00 – Coffee Break

15.30 – NON-INVASIVE PRENATAL TESTING AND DIAGNOSIS (continued)

Non-Invasive Prenatal Diagnosis of Single Gene Disorders
Dr. Natalie Chandler (England)

High-Resolution Non-Invasive Cell-Free DNA Sequencing in Pregnancy
Dr. Ieva Miceikaite (USA)

Chairs: Dr. Marie Balslev-Harder and Dr. Sofie Lindgren Christiansen

16.45–17.00 – END OF DAY 1

19.00 – CONFERENCE DINNER

DAY 2

8.30 – CELL-FREE DNA BIOLOGY AND PRE-ANALYTICS

DNA outside of cells is extracellular, but not cell-free
Prof. Peter Celec (Slovakia)

New high accuracy diagnostics for Aspergillus fumigatus infection in Zoo-housed birds using cell-free DNA and machine learning prediction
Dr. Markus Hodal Drag (Denmark)

Oral Presentations (5 min)
F. Evaluating cfDNA Quality from cerebrospinal fluid (CSF): A comparison of Extraction Kits with highly multiplexed droplet digital PCR (ddPCR). Flavia Matos Santo (England)
G. cfDNA responses to exercise differ by sex – considerations for liquid biopsy biomarker research. Kira Enders (Germany)

Chairs: Dr. Steffen Ullitz Thorsen and Dr. Sofie Lindgren Christiansen

10.10 – Coffee Break

10.40 – CELL-FREE BIOLOGY AND PRE-ANALYTICS

Integrative multiparametric analysis of circulating cell-free nucleic acids of plasma during aging
Dr. Nicolas Tessier (France)

Cell type signatures in cell-free DNA fragmentation profiles
Dr. Kate E Stanley (England)

Chairs: Dr. Marie Balslev-Harder and Prof. Peter Celec

12.00 – Lunch Break

13.00 – CELL-FREE DNA AND CANCER

Towards multi-modal liquid biopsy
Dr. Florent Mouliere (England)

Fragmentomics analysis of plasma DNA for cancer detection
Prof. Wai Kei Jacky Lam (Hong Kong)

Oral Presentation (5 min)
H. Standardization of purification, detection, and reporting results of ctDNA analyses. Søren Egstrand (Denmark)

Chairs: Prof. Peter Celec and Dr. Klaus Rieneck

14.30 – Coffee Break

15.00 – CELL-FREE DNA AND TRANSPLANTATION

Cell-Free DNA as Marker for Organ Health
Dr. Sean Agbor-Enoh (USA)

ddPCR-Based Testing of Donor-Derived Cell-Free DNA in Heart Transplantation Patients
Dr. Jens Böhmer (Sweden)

Oral Presentations (5 min)
I. Clinical relevance of donor-derived cell free DNA quantification and fragmentome study for the identification of events 3 months after lung transplantation. Alizée Sebastian (France)
J. Inter- and intra-individual variability of donor-derived cell-free DNA in stable kidney and liver transplant recipients. Fanny Sandberg (Switzerland)
K. Mapping Cell-Free DNA Tissue Origin in Transplant Recipients Through Methylation Signatures. Nicholas Küng (Switzerland)

Chairs: Dr. Hans Henrik Lawaetz Schultz and Dr. Frederik Banch Clausen

16.40 – POSTER AND GRANT AWARDS
Chair: Dr. Steffen Ullitz Thorsen (Denmark)

16.50-17.00 – CONFERENCE ENDS